Salem at East Liverpool

7:30 p.m., Friday

Salem’s football team is riding an 11-game out-of-conference winning streak dating back to 2016. The Quakers (2-0) have also won five straight against the Potters. East Liverpool (1-1) dropped a key Buckeye 8 game against Indian Creek last week.

Brookfield at United

7 p.m., Friday

Brookfield (1-1) was favored to be the front-runner in the All-American Conference but suffered a 49-28 to surging Springfield Local last week. United (1-1) is out of its two-week swing of Eastern Buckeye Conference opponents. A three-week road trek awaits the Eagles after this game.

Columbiana at Springfield

7 p.m., Friday

A lot of computer points are riding on this key Region 21, Div. VI matchup between the 2-0 Tigers and 1-1 Clippers. Springfield, the clear favorite in the Mahoning Valley Athletic Conference, missed the playoffs after going 9-1 a season ago. Columbiana has not beat Springfield since 2015 and will have to be wary of looking ahead to next week’s EOAC battle with Southern.

East Palestine at Campbell

7 p.m., Friday

East Palestine (0-2) has been outscored 111-0 so far this season, but Campbell (1-1) has once in its last 12. The Bulldogs bested the Red Devils in a shootout 48-37 last season. The will be the third straight game on turf for the Bulldogs this season.

Malvern at Wellsville

7 p.m., Friday

Things are looking up for the Tigers (2-0) after a 41-7 win over Div. V Edison last Friday. Last season the Tigers edged out the Hornets (1-1) by one. A win here sets the stage for a good run with a very favorable schedule ahead for Wellsville.

Leetonia at Southington

7 p.m., Friday

Leetonia (2-0) has got its footing after comfortable wins against Div. VII Sebring and Mathews to open the season. Southington (0-2) has given up 70 points total in two competitive losses.

Crestview at McDonald

7 p.m., Friday

Before the season, one would think this would be a possible matchup of two traditional powerhouses, but that’s not the case this time. Both teams were humbled last week and at 0-2 are both trying to get back on track.

Beaver Local at Minerva

7 p.m., Friday

Could this be it? By virtue of Buckeye Local snapping its 43-game losing streak last Friday, Minerva now owns Ohio’s longest current losing streak at 42 games. The Lions (0-2) are close though after losing the first two games by a combined 16 points. Beaver (1-1) will have to be careful after unexpectedly losing to Akron Kenmore-Garfield last week.

Struthers at West Branch

7 p.m., Friday

Struthers (1-1) and West Branch (0-2) were briefly in a conference together as members of the defunct Mahoning Valley Conference from 1979-81. There’s no conference glory on the line here, but this will be an important game as both teams look to break free of disappointing starts.

South Range at Canton Central Catholic

7 p.m., Friday

There will be a lot of points on the line in Div. V, Region 17. The region already has 10 2-0 teams and the Raiders (1-1) can’t afford to fall farther behind with a much tougher Northeast 8 conference schedule ahead. The Crusaders (1-1) lost to a powerhouse Perry team in the opener, but bounced back to beat Norwayne last week.

Mathews at Sebring

7 p.m. Friday

Mathews (1-1) bailed on Leetonia in the third quarter last week due to mounting injuries, so could this mean the Trojans (1-1) have a shot at their first winning streak since 2016?

Western Reserve at Norwayne

7 p.m., Friday

The Blue Devils (1-1) had no trouble with East Palestine last week, but it’s hard to predict what awaits them in Wayne County. Norwayne (0-2) took Mogadore to the wire in the first week and was blown out by Canton Central last week.

Buckeye Local at Oak Glen

7 p.m., Friday

Oak Glen (2-0) is off to its best start since 2012 behind its explosive offense. The Golden Bears can’t sleep on the Panthers as the team snapped its 43-game winning streak last week against Union Local.

Lisbon vs. Valley Christian at Poland

7 p.m., Saturday

Lisbon (0-2) has lost six straight and has been shutout four times in those losses including a 33-0 defeat vs. Mineral Ridge last week. Valley Christian (0-2) has scored six points in each of its defeats and is riding a seven-game losing streak. And oh yeah, the Eagles were a playoff team last season.

Steubenville Central at Southern

7 p.m., Saturday

Southern (2-0) took care of business against the Crusaders last season in a 26-13 win on the road. The Indians have many of the same pieces in place this time around but the Crusaders (1-1) have a winning pedigree. On a side note, Southern’s non-league opponents are a combined 1-7 so far so the Indians may have little room for error when it comes to making the playoffs.