Columbiana at Lisbon,

7 p.m., Friday

WHAT’S AT STAKE: Lisbon (6-1, 4-0 Eastern Ohio Athletic Conference) and Columbiana (5-2, 4-0) are not strangers when it comes to playing big league games. While this one won’t decide the EOAC yet, the winner will be in the driver’s seat for the championship and possibly the playoffs.

Toronto at East Palestine,

7 p.m., Friday

WHAT’S AT STAKE: East Palestine (5-2, 4-0) has been the area’s best offense at 42.6 points per game. Toronto (4-3, 2-2) started the season well, but the Red Knights were subsequently mercy-ruled against Eastern Ohio Athletic Conference leaders Columbiana and Lisbon. East Palestine High School graduate and Toronto coach Eric Meek will coach in his first game at his alma mater since 2002.

Southern at Wellsville,

7 p.m., Friday

WHAT’S AT STAKE: Southern (3-4, 1-3 in the Eastern Ohio Athletic Conference) and Wellsville (1-6, 0-4) are basically playing for pride at this point as the league and playoff races are well out of both team’s hands. Southern has not beaten Wellsville since 2012 and none of those Tiger wins in the streak were close games.

Leetonia at United,

7 p.m., Friday

WHAT’S AT STAKE: Believe it or not, United (3-4, 1-3 EOAC) has not faced Leetonia (0-7, 0-5) since 2005. The Eagles also have not beaten the Bears since 2003. Now’s as good as time as any to get reacquainted.

Crestview at Kent Roosevelt,

7 p.m., Friday

WHAT’S AT STAKE: Crestview (3-4) still isn’t officially eliminated from playoff contention, so the Rebels technically have something to play for against Div. II Kent Roosevelt (2-5). The Rough Riders have played all Div. III teams or above, so it could be another test of Crestview’s depth.

Beaver Local at Indian Creek,

7 p.m., Friday

WHAT’S AT STAKE: Beaver Local (6-1) has a chance to lock up the Buckeye 8 North Division title with a win over the Redskins (4-3). Creek has won the last three Buckeye 8 encounters against the Beavers, but those have been by a total of 15 points. A win would also go along way to putting the Beavers in the playoffs for the first time since 2005.

East Liverpool at Buckeye,

7 p.m., Friday

WHAT’S AT STAKE: Buckeye Local’s last win came on Oct. 17, 2014 against East Liverpool (2-5). The Panthers (0-7) aren’t likely to break a 29-game losing streak here, but the Potters had better be on guard.

Minerva at Salem,

7 p.m., Friday

WHAT’S AT STAKE: Salem (4-3, 1-3 in the Northeastern Buckeye Conference) is trying to pull out of a tailspin. The Quakers have lost three straight and have seen their possiblity of challenging for the final edition of the NBC go by the wayside. Minerva (0-7, 0-4) has seen better days as its losing streak is at 27.

Louisville at West Branch,

7 p.m., Friday

WHAT’S AT STAKE: It’s been nearly 50 years since these two teams started playing. It appears this will be the last meeting for the time being between the Leopards (3-4, 3-1 in the Northeastern Buckeye Conference) and Warriors (3-4, 2-2). Louisville holds a 25-7 advantage in the series. West Branch last won in 2012.

Akron Kenmore at South Range,

7 p.m., Friday

WHAT’S AT STAKE: South Range (7-0) is well on its way to the playoffs in Div. V, Region 17. The Raiders are also doing their part off the field as well. This week the team purchased 72 T-shirts to help support Akron Manchester quarterback Robbie Wagner who was nearly paralyzed by a hit against Northwest. Kenmore, by the way, is 0-7.

Sebring at McDonald, 7 p.m. Friday

WHAT’S AT STAKE: McDonald (6-1, 4-0) has not officially locked up a share of the Mahoning Valley Athletic Conference, but by virtue of a schedule including winless Sebring this week and Lowellville in the finale things are looking up for the Blue Devils who hold a one-game advantage over Western Reserve and Springfield.

Mineral Ridge at Springfield,

7 p.m, Friday.

WHAT’S AT STAKE: Beginning with this week’s game against Mineral Ridge (4-3, 2-2), Springfield (4-3, 3-1) closes out the season with three games in which the Tigers will be heavily favored to win. The only question left for the Tigers is one of computer points. The Tigers sit 13th in the highly competitive Div. VI, Region 21.

Oak Glen at Harrison Central,

7 p.m., Friday

WHAT’S AT STAKE: Oak Glen (2-4) is going through a rough patch and even though Harrison Central is 2-5 one the Huskies’ wins was a 41-0 victory over Edison — a team that beat the Bears 26-14 on Sept. 29.